Website review: Glioblastoma Brain Cancer Treatm...
amyss120 discovered this in Cancer
•2 reviews since Jan 22, 2008
cancer
•amyshah.com/cancer/glioblastoma-brain-cancer-...
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amyss120 discovered 6 months ago- Researchers at Dartmouth College have discovered a breakthrough chemical that successfully identifies and prevents brain cancer cells from undergoing mitosis.
- kismet72 rated 6 months ago
- Glioblastoma, with an average survival rate of only five years, is the most common and aggressive type of brain tumor. It affects over 50% of all brain tumor victims and is infamous for being highly resistant to traditional cancer therapies, such as radiotherapy, chemotherapy, and surgery. Dr. Gordon Gribble of Dartmouth College has lead a team of researchers to discovering a high performance compound that can kill 50% of glioblastoma cells at its lowest dosages. In experiments run so far, this recently patented drug can out-perform current anti-brain cancer drugs on the market such as Procarbazine, Nitrosourea, and Carmustine. This new drug has a cytotoxic effect on cancerous cells by binding tightly to their DNA and poisoning the cell through a process called bis-intercalation, in which the DNA is double-binded and the cell cannot replicate because its DNA fails to unravel (due to the double binding of the two strands of DNA). The figure above shows a green molecule bis-intercalated to DNA. This demonstrates how the nucleotides can adjust their bonding in reaction to a chemical reagent. The researchers are continuing to perform in vitro studie
