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•6 reviews since Nov 1, 2006
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•sciencenow.sciencemag.org/cgi/content/full/20...
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Reviews of this website

potatoheadbobby rated 22 months ago- Why does the idea of resurrecting long dead viruses strike me as a decidedly bad idea?

Olgui rated 22 months ago
Viral fossil resurrected From the page: In a controversial study, researchers have resurrected a retrovirus that infected our ancestors millions of years ago and now sits frozen in the human genome. Published online by Genome Research this week, the study may shed new light on the history of these genomic intruders, as well as their role in tumors. Although this particular virus, dubbed Phoenix, is a wimpy one, some argue that resuscitating any ancient virus is inherently risky and that the study should have undergone stricter reviews. Retroviruses have the ability to make DNA copies of their RNA genomes and incorporate these into the host's genome. If this happens in a germ cell, the copy can be passed on to future generations. Indeed, the human genome is littered with the remnants of such human endogenous retroviruses (HERVs). So far, researchers had been unable to recover a complete, functional HERV from a human genome however; part of the reason, they assumed, was that mutations accumulated over the millennia had rendered such viruses dysfunctional. image: Electron microscopy pictures show how the Phoenix virus, when infecting human cells, forms particles at the cell membrane. Credit: Dewannieux et al., Genome Research

Raytracer rated 22 months ago- From the page: "In a controversial study, researchers have resurrected a retrovirus that infected our ancestors millions of years ago and now sits frozen in the human genome. Published online by Genome Research this week, the study may shed new light on the history of these genomic intruders, as well as their role in tumors. Although this particular virus, dubbed Phoenix, is a wimpy one, some argue that resuscitating any ancient virus is inherently risky and that the study should have undergone stricter reviews."

CloudsSansWater rated 22 months ago- Come the plague, the biologists will be the first up against the wall!
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