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 kaolelo rated 4 months ago-
A biotech company, founded by researchers from the University of Munich, has developed a fascinating way to make the immune system fight cancer.
On Thursday, Micromet Inc. announced that its experimental drug, MT103, had impressive results in a test upon seven Non-Hodgkin's Lymphoma patients. All of them had failed at least three conventional treatments, but showed signs of recovery after receiving doses of a two-headed antibody.
BiTE antibodies, or bispecific T cell engagers, are highly-engineered biological molecules with sticky ends. One side can cling to CD19, a protein found on cancerous B cells, and the other half can grab onto CD3, which is found on cytotoxic T cells. By momentarily drawing those cells together, the drug can coax the cytotoxic T cells into fighting the disease.
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