Regrowing Tissues Like Newt
By shutting off a single gene, researchers think humans could regenerate damaged tissue just as newts do. J. Carmichael
From the page:
Essentially, switching off the p21 gene allows adult cells to behave like pluripotent stem cells, reorienting themselves into whatever kind of tissue they need to be. But naturally there is a give-and-take; p21 is closely intertwined with another gene, p53, a cell-division regulator that, if allowed to run amok, can lead to many types of cancers. The p21 gene acts as a safety valve for p53, stopping cell division in the case of DNA damage.
Yeah, let's do that.
I'm not sure how I feel about gene modification...It's very dystopian in a sense...
Take this with a bowl of salt. The magazine calls itself 'Popular Science'.
From the page: "However, in the p21-free lab mice there was no cancer surge as one might expect, but rather an increase in apoptosis, or cell suicide, which directs damaged cells to destroy themselves."
Knocking out a single gene (p21) allows tissue to regenerate WITHOUT causing tumors. Of course making knock-out humans (lol) would raise some ethical issues, so on to develop a p21 inhibitor?
From the page: "Regrowing Tissues Like Newts By shutting off a single gene, researchers think humans could regenerate damaged tissue just as newts do."