I'll go ahead and predict that self-controlled evolution will be the next major field of biology and medicine. If we can target the genes that are major contributors to health issues such as diabetes, obesity, cancer, heart disease, etc, we could solve these problems orders of magnitude faster than natural selection could. The main issue is how to make the changes on a large scale and make it affordable. Granted when I say large scale, it's not like it needs to be 100% of the population. 5-10% would probably be enough.